Diabetic foot syndrome

Diabetic foot syndrome.

Themost significant consequences of diabetic foot problems are ulcerations and amputations. ▶ Between 0.8 and 10% of all people with diabetes mellitus suffer from a foot ulcer. ▶ The annual rate of new diabetic foot cases is between 2.2 and 5.9 %. ▶ Germany is in the upper range of European countries with its rate of over 60000 amputations per year. Approximately 70% of all amputations are perf...

Neuropathy and Diabetic Foot Syndrome

Diabetic foot ulceration is a serious complication of diabetes mellitus worldwide and the most common cause of hospitalization in diabetic patients. The etiology of diabetic foot ulcerations is complex due to their multifactorial nature; in the pathophysiology of diabetic foot ulceration polyneuropathy is important. Proper adherence to standard treatment strategies and interdisciplinary coopera...

Diabetic foot syndrome--dermatological point of view.

Patients with diabetes mellitus often suffer from diabetic foot syndrome, a condition leading to foot ulceration or even amputation of lower extremity. Peripheral neuropathy combined with repetitive trauma to the foot and peripheral vascular disease are the main etiological factors in the development of foot ulcers. Other major contributive factors include the effects of callus, increased plant...

Endothelial progenitor cells in diabetic foot syndrome.

In the late 20th century endothelial progenitor cells (EPCs) were discovered and identified as cells capable of differentiating into endothelial cells. Antigens characteristic of endothelial cells and hematopoietic cells are located on their surface. EPCs can proliferate, adhere, migrate and have the specific ability to form vascular structure, and they have a wide range of roles: They particip...

Diabetic foot